Possible Zlob Trojan Removal…?
There is a red circle with an "X" in it on my taskbar. My screen resolution drops (making everything bigger) and a Fatal Error pops up informing me that I need to upgrade my Media Codecs for Media Player (obviously virus). I’ve done my homework on Zlob Tojans G and Media Codec Viruses but still can’t find a way to completely remove it. I’ve used Safe Mode and scanned with: Spybot Seek and Destroy, Ad-Aware, FixIEDef, NOD32 and SmitfraudFix… I can’t bring up Task Manager by pushing CTRL+ALT+DEL or CTRL+SHFT+ESC or by the "Run" function in the start menu…. There aren’t any pop-ups yet(Thank god) or redirections online. Just media errors and elephantitis of screen.
*Like I said I’ve done a little bit of homework on what I’m dealing with so please refrain from explaining to me what a Trojan virus "is", believe me I know.*
Any help would be much appreciated. I also don’t want any "spyware removal advertisers" replying wasting my time…I’m not shelling out any dough for something that should be free. Thank You! 
Thanks Timbuk4! …Malwarebytes was awesome.. it cleared what others couldn’t… Now I’ve just got a problem with my sound (There is none.) … Is that common afterwards.. how can I restore it?
A Trojan horse, or trojan for short, is a term used to describe malware that appears, to the user, to perform a desirable function but, in fact, facilitates unauthorized access to the user’s computer system. The term comes from the Trojan Horse story in Greek mythology. Trojan horses are not self-replicating which distinguishes them from viruses and worms. Additionally, they require interaction with a hacker to fulfil their purpose. The hacker need not be the individual responsible for distributing the Trojan horse. It is possible for hackers to scan computers on a network using a port scanner in the hope of finding one with a Trojan horse installe.
http://trojan-horses-killer.com
http://malwarebytes.org
Then try a System Restore to get settings back to normal – back to before the trojan hit.